Gene Expression Analysis

Gene expression microarray technology has been responsible for much of the functional genomics data generated in recent years. These data promise to help researchers investigate the regulation and transcription of genes, which is vital for understanding the ultimate roles that proteins play within cells as well as developing diagnostic tests and finding new drug targets. Microarray data can be particularly difficult to analyze and comprehend due to unusual noise characteristics and variation between protocols and technologies. We are developing methods to harness large collections of microarray data that make it more accessible to researchers. Also, our approaches are readily adaptable to new technologies that can measure transcription, such as deep sequencing approaches.

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